Vaccine Tech 30 Years in the Making Is Getting Put to the Ultimate Test

The coronavirus pandemic could change the way we make vaccines

Emily Mullin
Future Human

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Photo: SOPA Images/Getty Images

In September 1992, Deborah Fuller traveled from Wisconsin to New York for a scientific conference at the nonprofit Cold Spring Harbor Laboratory, brimming with anticipation. She was there to present early but promising research on a completely new vaccine approach that she had been working on.

It turned out to be a fortuitous meeting. “I go there thinking I’m going to be the only one with this new idea, and there were half a dozen other people all presenting this concept,” says Fuller, PhD, now a professor of microbiology at the University of Washington School of Medicine in Seattle who’s working on a coronavirus vaccine. If other labs were getting the same results, it meant her research wasn’t just a fluke.

The conference organizers were riveted by the new idea. They reshuffled the meeting schedule so that Fuller and the others could present their research during the same session, on the last day of the meeting. Scientists who planned to leave the conference early scrambled to reschedule their flights home so they could stick around to hear about it.

The idea was elegant: Deliver a set of instructions that tells the body’s own cells to make a…

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Emily Mullin
Future Human

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.